Take Oscillo at the First Sign of Flu! Oscillococcinum (o - sill - cox - see - num) is safe, natural and easy to take. Oscillococcinum, an FDA drug - regulated, over - the - counter homeopathic flu medicine, is currently available in 43 countries. Oscillo is the #1 OTC flu medicine in France and the #1 homeopathic flu medicine in the United States. Clinical trials have shown that when taken at the first sign of flu, 63 percent of Oscillo users showed clear improvement within 48 hours; so keep a box on hand!