Nature"s Way Grapefruit Seed (Citrus paradisi) is standardized to a 12:1 concentrate. It contains compounds that provide broad-spectrum intestinal health benefits. Grapefruit seed extract is a highly concentrated fungal and microbial balancing extract. Grapefruit seed extract exerts these effects within the gastrointestinal (GI) tract, promoting healthy microflora and gut ecology. A preliminary clinical trial reported that grapefruit seed extract supplements helped support healthy GI function and comfort. An in vitro study using human skin fibroblast cells indicated that grapefruit seed extract promoted healthy gram-positive and gram-negative balance. Other studies support these findings, citing that grapefruit seed extract promotes a healthy environment when exposed to a wide range of bacterial biotypes. Health & longevity through the healing power of nature - that is what it means to Trust the Leaf(R)