There is substantial effort and research within various disciplines to tackle the current issues and trends in instructional systems and technology that deal with the improvement of computer- and technology-assisted learning settings and environments, online and distance education, technology and cognition, as well as the multicultural and cross-cultural aspects of instructional technology and learning. The Handbook of Research on Instructional Systems and Technology addresses these issues by providing information on the different styles of instructional design methodologies, tips, and strategies on how to use technology to facilitate active learning as well as techniques to help faculty and researchers develop online instructional and teaching materials. This Handbook of Research enables libraries to provide a foundational reference to meet the information needs of researchers, educators, practitioners, administrators, and all other stakeholders in the context of instructional systems and technology.