The increasing incidence of esophageal adenocarcinoma has created an enormous interest and stimulus for research in this area. GERD brings together, for the first time, a vast amount of disparate literature and documents the entire pathogenesis of reflux disease in one place. The book presents reflux carditis as a new diagnostic criterion of GERD and for the first time defines the dilated end-stage esophagus and the earliest microscopic phase of GERD that is missed by present diagnostic criteria. GERD presents both clinical and pathological information and is meant to be used as a comprehensive reference for gastroenterologists, esophageal surgeons, and pathologists alike. *Outlines how gastroesophageal reflux causes cellular changes in the esophagus *Brings together the pathogenesis of the disease in one source and applies it toward clinical treatment *Tom DeMeester is THE leading international expert on reflux disease; Parakrama Chandrasoma is one of the leading pathologists in the area *Book contains approximately 350 illustrations *Ancillary web site features color illustrations: www.chandrasoma.com