Clinique Dramatically Different Moisturizing Lotion 4.2 fl oz. The moisture "drink? developed by Clinique"s dermatologists to maintain optimal moisture balance for very dry skins, or skins dry in the cheeks, comfortable to oily in the T-zone. Softens, smooths, improves. Directions: Apply twice a day to face and throat all over, or where needed. For best results use after Facial Soap and Clarifying Lotion.