Give Advance Dental Chews to clean your dog"s teeth and maintain your dog"s health. These chews contain 100% edible toothpaste cleaners within the chew. The surface is coated with additional dry edible canine toothpaste tartar control formula. The chew is entirely digestible. Also contains dried beef meat and bone meal, dried chicken liver, corn starch and rice. It is guaranteed Salmonella free and does not contain rawhide, fluoride or human toothpaste surfactants. Directions: Give as a treat 3 to 7 times weekly to help reduce tartar buildup. Sizes, Shapes, and Quantity: Small: - 1 3/8" x 3/8 - Round - 20 count, Large: - 6 1/2" x 3" x 1/2" - Oval - 6 count, Medium: - 2 5/8" x 5/8" - Ring - 10 count