Temperature measurement is an integral part of many process industries. Thus it is essential to have a competent system for this measurement purpose. We deals with the design and implementation of a Personal Computer (PC) based temperature measurement system. The main sensor used in this case is a commercially available thermistor and custom-made signal conditioning hardware and a data acquisition system. The distinct advantage of this system is its cost effectiveness when compared with conventional temperature measurement systems frequently employed various processes. The thermistor output is a single ended voltage, which is dependent on the transfer function of the thermistor itself. According to this transfer function, the thermistor provides a certain voltage for a certain temperature. The output of the thermistor is then amplified using a non-inverting instrumentation amplifier. Then the instrumentation amplifier output signal is fed to an Analog-to-digital converter (ADC) that...