The association between Anemia of Chronic Disease (ACD)and chronic periodontitis has been studied with varying results .In the earlier studies it was reported that anemia plays a direct role in the etiology of periodontal disease . On the contrary, it has been demonstrated that anemia occurred as a result of destructive periodontal disease by means of chronic inflammation.This separate entity was termed as Anemia of Chronic Disease.Therefore in the present study, an attempt was made to explore a link between chronic periodontitis and anemia of chronic disease by evaluating certain hematologic markers indicative of ACD .