This revised and expanded edition highlights the importance of understanding the biologic and psychologic pain mechanisms to prepare clinicians who treat patients presenting with a variety of pain symptoms. In addition to presenting objective definitions and descriptions of pain and its physical effects, the authors include evidence-based research on how the pain experience may be influenced by genetics, gender, or individual psychosocial and health histories. Extending well beyond basic toothache and TMDs, this book covers pathologic conditions of surrounding orofacial structures and nonodontogenic pain disorders that may manifest as orofacial pain as well, including new chapters on headache and orofacial pain related movement disorders. Chapters on management guide clinicians on how to develop practical and compassionate treatment plans based on logical evaluation methods, accurate diagnosis, and appropriate pharmacologic treatment, or how to decide when referral to other health care providers is warranted. A series of case studies demonstrates the effective application of this information to clinical situations. Contents 1 What is Pain and How Do We Classify Orofacial Pain? - Charles McNeill, DDS, Ronald Dubner, DDS, PhD, Alain Woda DDS, PhD 2 Epidemiology of Orofacial Pain: Prevalence, Incidence, and Risk Factors - Linda LeResche, ScD, Mark Drangsholt, DDS, PhD 3 Current Beliefs and Educational Guidelines - Charles G. Widmer, DDS, MS 4 Peripheral Mechanisms of Orofacial Pain - Bruce Matthews, BDS, PhD, Barry J. Sessle, BDS, MDS, BSc, PhD, FRSC 5 Central Nociceptive Pathways - B. Sessle, BDS, MDS, BSc, PhD, FRSC, Koichi Iwata, DDS, PhD, R. Dubner, DDS, PhD 6 Neurochemical Factors in Injury and Inflammation of Orofacial Tissues - Asma A. Khan, BDS, PhD, Ke Ren, DDS, PhD, Kenneth M. Hargreaves, DDS, PhD 7 Mechanisms of Neuropathic Pain - Alain Woda, DDS, PhD, Michael W. Salter, MD, PhD 8 Pain Modulatory Systems - William Maixner, DDS, PhD 9 Pain and Genetics - Ze"ev Seltzer, DMD, Jeffrey S. Mogil, PhD 10 Measurement of Pain - Pierre Rainville, PhD 11 Psychologic State and Pain Perception - Petra Schweinhardt, Marco L. Loggia, Chantal Villemure, M. Catherine Bushnell 12 Psychosocial Issues - Samuel F. Dworkin, DDS, PhD 13 Pain and Gender - Thuan T.T. Dao, DMD, MSc, PhD, FRCD(C) 14 Pain and Motor Reflexes - James P. Lund, BDS, PhD, Greg Murray, BDS, MDS, PhD, FRACDS, Peter Svensson, DDS, PhD, Dr Odont 15 Persistent Pain and Motor Dysfunction - J. Lund, BDS, PhD 16 Pain and Sleep Disturbances - Gilles J. Lavigne, DMD, FRCD(c), PhD, Takafumi Kato, DDS, PhD, Pierre Mayer, MD, FRCP(c) 17 The Path to Diagnosis - Jean-Paul Goulet, DDS, MSD, FRCD(c), Sandro Palla, Dr Med Dent 18 Evidence-Based Pain Management - Jocelyne S. Feine, DDS, HDR 19 Management of Persistent Orofacial Pain - Christian S. Stohler, DDS, Dr Med Dent 20 Management of Dental Pain - G. Rex Holland, BSc, BDS, PhD 21 Management of Inflammatory Pain - Sharon M. Gordon, DDS, MPH, PhD, Raymond A. Dionne, DDS, PhD 22 Management of Masticatory Myalgia and Arthralgia - James R. Fricton, DDS, MS, Eric L. Schiffman, DDS, MS 23 Management of Mucosal Pain - Edmond Truelove, DDS, MSD 24 Management of Neuropathic Pain - Eli Eliav DMD PhD, Mitchell B. Max, MD 25 Management of Orofacial Pain Related to Headache: Principles and Practice - Jeffrey P. Okeson, MD 26 Management of Movement Disorders Related to Orofacial Pain: Principles and Practice - Frank Lobbezoo, DDS, PhD, Pierre Blanchet, MD, FRCP(C), PhD, G. Lavigne, DMD, PhD, FRCD(C) 27 Illustrative Case Reports - Antoon De Laat, LDS, GHO, Sandro Palla, Dr Med Dent, José Tadeu Tesseroli de Siqueira, DDS, PhD, Yoshiki Imamura, DDS, PhD 28 Science Transfer in Orofacial Pain: Problems and Solutions - Charles S. Greene, BS, DDS