This book presents an overview of the use of contemporary regenerative techniques in the treatment of periodontal osseous and soft tissue defects. Each chapter is designed to cover an important aspect related to periodontal regeneration, including an understanding of periodontium anatomy, biologic wound healing, regenerative materials, surgical techniques, and clinical applications. By focusing on the most relevant regenerative materials and procedures, the authors present effective treatment paradigms that incorporate biologic concepts and biomaterial enhancements with predictable surgical techniques. Well-documented clinical cases emphasize the management of critical treatment factors as well as the use of proven techniques that can optimize treatment outcomes. A must-read for any practitioner with an interest in the rationale, possibilities, and limitations of regenerative procedures of periodontal therapy. Contents 1. Introduction A. Sculean and A. Stavropoulos 2. Anatomy of the Periodontium in Health and Disease D. Bosshardt 3. Periodontal Wound Healing/Regeneration U. Wikesjö, G. Polimeni, A. Xiropaidis, and A. Stavropoulos 4. Guided Tissue Regeneration: Biological Concept and Clinical Application in Intrabony Defects A. Stavropoulos, P. Windisch, I. Gera, and A. Sculean 5. Guided Tissue Regeneration: Application in Furcation Defects P. Eickholz and S. Jepsen 6. The Biological Background of Emdogain l. Hammarström, A. Sculean, and S. P. Lyngstadaas 7. Application of Enamel Matrix Proteins in Intrabony Defects: A Biology-Based Regenerative Treatment L. Heijl and A. Sculean 8. Application of Enamel Matrix Proteins in Furcation Defects N. Donos, L. Heijl, and S. Jepsen 9. Treatment of Gingival Recession Using Guided Tissue Regeneration or Emdogain K. Jepsen, B. Heinz, S. Hägewald, and S. Jepsen 10. Role of Grafting Materials in Regenerative Periodontal Therapy A. Sculean, P. Windisch, and A. Stavropoulos 11. Combination Strategies to Enhance Regenerative Periodontal Surgery A. Sculean, D. Nikolidakis, G. Chiantella, F. Schwarz, and A. Stavropoulos 12. Clinical Applications and Techniques in Regenerative Periodontal Therapy C. Nemcovsky 13. Periodontal Tissue Engineering: Focus on Growth Factors A. Stavropoulos and U. Wikesjö 14. New Experimental Approaches Towards Periodontal Regeneration M. Weinreb 15. Prognostic and Risk Factors for Periodontal Regenerative Therapy P. Eickholz 16. Flap Design and Suturing Techniques to Optimize Reconstructive Outcomes L. Trombelli 17. Periodontal Regeneration: Surgical Risk of Complications and New Surgical Trends D. Etienne, R. Azzi, S. Aroca 18. Microsurgical Techniques in Regenerative Periodontal Therapy H. Wachtel, S. Fickl, T. Thalmair, and W. Bolz