BioSpot Defense Flea and Tick SpotOn with Smart Shield Applicator is available in 5 weight ranges. BioSpot Defense starts killing fleas and ticks within 15 minutes and kills all flea life stages: eggs, larvae, and adults. The product is water resistant in humid and wet conditions. The new applicator, which is included, delivers the dosage in an easy, efficient and safe manner. This package contains a 6-month supply.