Dietary Supplement. Made with CLA One. Optimum Nutrition"s CLA Softgels are validated to contain a minimum of 1,000 mg of CLA One per softgel. [1,000 mg of CLA One yields 750 mg of total CLA, of which 700 mg are active isomers.] Optimum Nutrition"s CLA Softgels are packaged in our own state-of-the-art, OTC approved manufacturing facility in accordance with current Good Manufacturing Practices (cGMP"s).