Big game hunter Bob Rainsford is shipwrecked off a remote island and manages to reach safety. He discovers the island is owned by reclusive Count Zaroff, who is also interested in big game hunting, but he prefers his prey to be humans. Soon Bob and Eve Trowbridge are being chased by the count and his ferocious hounds. Made by the same team responsible for King Kong, The Most Dangerous Game shares many of the same eerie island sets.